SCHEMBL31723140

SCHEMBL31723140

Cc1cccc(-c2oc3cc(Cl)ccc3c(=O)c2C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
ALDH1A1 P00352 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
KDM4E B2RXH2 2/20 0.59
NPC1 O15118 1/20 0.59
HPGD P15428 1/20 0.59
HTT P42858 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
TTR P02766 3/20 0.49
MCL1 Q07820 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ANO1 Q5XXA6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20919306 1.00 MAPT (0.59) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28427581 0.91 MAPT (0.70) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31723150 0.91 MAPT (0.70) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28431175 0.90 MAPT (0.68) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31723158 0.90 MAPT (0.68) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31723151 0.86 TTR (0.49) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL22284777 0.86 TTR (0.49) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31723137 0.85 KDM4E (0.72) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28429262 0.85 KDM4E (0.72) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28433296 0.84 MAPT (0.63) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3699174-B1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2025-11-12 EP claimed