SCHEMBL31723174

SCHEMBL31723174

O=C(O)c1c(-c2ccc(Cl)cc2)oc2ccc(Cl)cc2c1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
ALDH1A1 P00352 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
KDM4E B2RXH2 2/20 0.61
HTT P42858 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
HPGD P15428 1/20 0.61
ADORA3 P0DMS8 2/20 0.59
TTR P02766 2/20 0.57
MKNK2 Q9HBH9 1/20 0.54
TP53 P04637 1/20 0.54
CSNK2A2 P19784 1/20 0.54
CSNK2B P67870 1/20 0.54
CSNK2A1 P68400 1/20 0.54
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA12 O43570 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20923370 1.00 MAPT (0.61) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL22284779 0.89 MAPT (0.79) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL31723112 0.89 MAPT (0.56) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL31723133 0.89 MAPT (0.79) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL20919316 0.89 MAPT (0.56) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL20919202 0.88 MAPT (0.52) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL31723136 0.88 MAPT (0.52) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL28427563 0.87 MEN1 (0.53) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL28429303 0.86 RET (0.63) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL20918175 0.84 ALDH1A1 (0.57) MAPTALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3699174-B1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2025-11-12 EP claimed