SCHEMBL31723201

SCHEMBL31723201

CNc1cc(C)cc(Nc2ccc(OC)c(F)c2)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.42
ABCB1 P08183 1/20 0.42
ABCC1 P33527 1/20 0.42
RAPGEF4 Q8WZA2 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
THRB P10828 2/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 3/20 0.39
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
TUBB1 Q9H4B7 1/20 0.38
NPC1 O15118 2/20 0.37
PIK3CA P42336 1/20 0.37
KCNQ3 O43525 1/20 0.37
KCNQ2 O43526 1/20 0.37
GALR2 O43603 2/20 0.37
GALR1 P47211 1/20 0.37
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454201 0.85 ABCG2 (0.41) ABCG2ABCB1ABCC1RAPGEF4SMN1; SMN2
SCHEMBL22231715 0.85 ABCG2 (0.41) ABCG2ABCB1ABCC1RAPGEF4SMN1; SMN2
SCHEMBL29454337 0.84 RAPGEF4 (0.53) RAPGEF4SMN1; SMN2HPGDRAB9AIDO1
SCHEMBL22232172 0.75 GALR2 (0.39) ABCG2ABCB1ABCC1RAPGEF4SMN1; SMN2
SCHEMBL22232170 0.75 GALR2 (0.39) ABCG2ABCB1ABCC1RAPGEF4SMN1; SMN2
SCHEMBL22232416 0.75 KCNH2 (0.43) RAPGEF4SMN1; SMN2THRBHPGDRAB9A
SCHEMBL31723248 0.75 BACE2 (0.41) ABCG2ABCB1ABCC1SMN1; SMN2THRB
SCHEMBL22232200 0.75 BACE2 (0.41) ABCG2ABCB1ABCC1SMN1; SMN2THRB
SCHEMBL31723235 0.75 KCNH2 (0.43) RAPGEF4SMN1; SMN2THRBHPGDRAB9A
SCHEMBL29454060 0.75 KCNH2 (0.43) RAPGEF4SMN1; SMN2THRBHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed