SCHEMBL31723230

SCHEMBL31723230

Cc1cc(N)c(Cl)c(Nc2ccc(F)c(F)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 5/20 0.51
GAA P10253 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
GFER P55789 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
IDO1 P14902 3/20 0.43
TDO2 P48775 2/20 0.40
DHFR P00374 2/20 0.39
SOS1 Q07889 1/20 0.39
APP P05067 1/20 0.37
TRPA1 O75762 1/20 0.36
PIK3CA P42336 1/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CHRNA7 P36544 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232610 1.00 RAPGEF4 (0.51) RAPGEF4GAAKDM4EMEN1GFER
SCHEMBL29454076 1.00 RAPGEF4 (0.51) RAPGEF4GAAKDM4EMEN1GFER
SCHEMBL22231715 0.85 ABCG2 (0.41) RAPGEF4IDO1TDO2PIK3CAMAPT
SCHEMBL29454060 0.85 KCNH2 (0.43) RAPGEF4IDO1TDO2PIK3CAMAPT
SCHEMBL22232416 0.85 KCNH2 (0.43) RAPGEF4IDO1TDO2PIK3CAMAPT
SCHEMBL31723235 0.85 KCNH2 (0.43) RAPGEF4IDO1TDO2PIK3CAMAPT
SCHEMBL29454201 0.85 ABCG2 (0.41) RAPGEF4IDO1TDO2PIK3CAMAPT
SCHEMBL22231721 0.84 BPTF (0.41) RAPGEF4GAAKDM4EMEN1GFER
SCHEMBL29454349 0.84 BPTF (0.41) RAPGEF4GAAKDM4EMEN1GFER
SCHEMBL22232474 0.84 NPC1 (0.44) RAPGEF4GAAKDM4EMEN1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed