Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.57 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | CDK4 | P11802 | 3/20 | 0.47 |
| ▸ | CCND3 | P30281 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987306 | 0.90 | PTPN11 (0.67) | PTPN11MAPK3MAPK1KCNH2 | |
| SCHEMBL31723336 | 0.90 | PTPN11 (0.56) | PTPN11MAPK3MAPK1KCNH2CDK4 | |
| SCHEMBL30111100 | 0.89 | PTPN11 (0.54) | PTPN11MAPK3MAPK1KCNH2CDK4 | |
| SCHEMBL24879085 | 0.89 | PTPN11 (0.54) | PTPN11MAPK3MAPK1KCNH2CDK4 | |
| SCHEMBL24879183 | 0.88 | PTPN11 (0.54) | PTPN11MAPK3MAPK1KCNH2CDK4 | |
| SCHEMBL24878906 | 0.88 | PTPN11 (0.54) | PTPN11MAPK3MAPK1KCNH2CDK4 | |
| SCHEMBL30111133 | 0.88 | PTPN11 (0.54) | PTPN11MAPK3MAPK1KCNH2CDK4 | |
| SCHEMBL31723346 | 0.88 | PTPN11 (0.57) | PTPN11MAPK3MAPK1KCNH2CDK4 | |
| SCHEMBL30987349 | 0.87 | PTPN11 (0.68) | PTPN11MAPK3MAPK1KCNH2 | |
| SCHEMBL30987334 | 0.87 | PTPN11 (0.53) | PTPN11MAPK3MAPK1KCNH2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |