⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311136 | 0.64 | — | — | |
| SCHEMBL14311997 | 0.64 | — | — | |
| Zinc Ion SCHEMBL3173043 | 0.62 | — | — | |
| SCHEMBL8431278 | 0.51 | LMNA (0.33) | — | |
| SCHEMBL27629935 | 0.51 | LMNA (0.33) | — | |
| SCHEMBL1082522 | 0.51 | — | — | |
| SCHEMBL18470 | 0.51 | — | — | |
| SCHEMBL7884727 | 0.51 | LMNA (0.33) | — | |
| SCHEMBL406120 | 0.51 | — | — | |
| SCHEMBL4394624 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100021561-A1 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | ALCON RESEARCH, LTD. | 2010-01-28 | — | — | US | claimed |
| WO-2008036855-A2 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | ALCON RESEARCH, LTD. (US) | 2008-03-27 | — | — | WO | claimed |
| EP-2066300-B2 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | NOVARTIS AG (CH) | 2019-01-23 | — | — | EP | disclosed |
| EP-2066300-B1 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | ALCON RES LTD (US) | 2015-06-17 | — | — | EP | disclosed |
| US-8388941-B2 | Self preserved aqueous pharmaceutical compositions | ALCON RESEARCH, LTD. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20100021562-A1 | SELF PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | NOVARTIS AG (CH) | 2010-01-28 | — | — | US | disclosed |
| US-20100021561-A1 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | ALCON RESEARCH, LTD. | 2010-01-28 | — | — | US | disclosed |
| CN-101522171-A | Self-preserved aqueous pharmaceutical compositions | ALCON MFG LTD (US) | 2009-09-02 | — | — | CN | disclosed |
| EP-2066300-A2 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | Alcon Research, Ltd. (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008042619-A2 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | ALCON RESEARCH, LTD. (US) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008036855-A2 | SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS | ALCON RESEARCH, LTD. (US) | 2008-03-27 | — | — | WO | disclosed |