SCHEMBL317253

SCHEMBL317253

Cc1cc(I)cc(C(=O)NC(C)(C)C)c1N

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.41
APEX1 P27695 1/20 0.41
KDM4E B2RXH2 3/20 0.39
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
ALOX5AP P20292 2/20 0.33
FEN1 P39748 2/20 0.33
JAK2 O60674 1/20 0.32
CHRM4 P08173 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20756954 0.83 POLB (0.42) POLBAPEX1KDM4EMAOAMAOB
SCHEMBL3664060 0.81 KDM4E (0.42) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL2131841 0.81 POLB (0.47) POLBAPEX1KDM4EMEN1KMT2A
SCHEMBL13361949 0.78 MAP2K1 (0.33) KDM4E
SCHEMBL1314957 0.77 KDM4E (0.39) KDM4EKMT2AALDH1A1HPGDJAK2
SCHEMBL1393663 0.77 KDM4E (0.41) POLBAPEX1KDM4EMAPTALDH1A1
SCHEMBL13377342 0.77 POLB (0.42) POLBAPEX1KDM4EMAOAMAOB
SCHEMBL857080 0.75 KDM4E (0.66) POLBAPEX1KDM4EMEN1KMT2A
SCHEMBL4605842 0.75 KDM4E (0.46) POLBKDM4EMAPTALDH1A1GAA
SCHEMBL25295693 0.75 KDM4E (0.47) POLBKDM4EMAPTALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790202-B2 Anthranilamide derivatives as pesticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-10-17 US disclosed
CN-103080102-B anthranilamide derivatives as pesticides 拜耳知识产权有限责任公司 2016-08-24 CN disclosed
EP-2590964-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES AS PESTICIDES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
EP-2590964-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVE AS A PESTICIDE Bayer Intellectual Property GmbH (DE) 2013-05-15 EP disclosed
WO-2012004208-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVE AS A PESTICIDE BAYER CROPSCIENCE AG (DE) 2012-01-12 WO disclosed
US-20120010250-A1 Anthranilamide derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010250-A1 Anthranilamide derivatives as pesticides ANTXR2, NQO2, AADAC POLB 4331/4885APEX1 1981/4885KDM4E 1453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.