Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314957 | 0.81 | KDM4E (0.39) | KDM4EHPGDJAK2MAPK14ALDH1A1 | |
| SCHEMBL317253 | 0.81 | POLB (0.41) | KDM4EGAAMAPTHPGDJAK2 | |
| SCHEMBL25356937 | 0.81 | CREBBP (0.35) | TP53IKBKBGAAMAPTNEU3 | |
| SCHEMBL4605842 | 0.79 | KDM4E (0.46) | KDM4ETP53GAAMAPTHPGD | |
| SCHEMBL857080 | 0.79 | KDM4E (0.66) | KDM4ETP53GAAMAPTHPGD | |
| SCHEMBL25295693 | 0.79 | KDM4E (0.47) | KDM4EGAAMAPTHPGDHSD17B10 | |
| SCHEMBL384330 | 0.79 | KDM4E (0.42) | KDM4EIKBKBGAAJAK2ALDH1A1 | |
| SCHEMBL634151 | 0.79 | KDM4E (0.42) | KDM4EIKBKBGAAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL30808427 | 0.77 | KDM4E (0.41) | KDM4EIKBKBGAAJAK2ALDH1A1 | |
| SCHEMBL31428183 | 0.75 | KDM4E (0.42) | KDM4ETP53IKBKBGAANEU3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231592-B1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | DU PONT (US) | 2016-02-17 | — | — | EP | disclosed |
| US-8247570-B2 | Process for preparing 2-amino-5-cyanobenzoic acid derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120130080-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | FMC CORPORATION | 2012-05-24 | — | — | US | disclosed |
| EP-2231592-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009085816-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130080-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | C9, CLIC4, C5 | KDM4E 1061/4885TP53 4486/4885IKBKB 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.