Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 0.80 |
| ▸ | DDX5 | P17844 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | HBB | P68871 | 2/20 | 0.71 |
| ▸ | CASP1 | P29466 | 1/20 | 0.71 |
| ▸ | CASP7 | P55210 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | STAT6 | P42226 | 1/20 | 0.71 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30538213 | 0.97 | TOP1 (0.82) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL26405346 | 0.97 | TOP1 (0.82) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL3138027 | 0.93 | TOP1 (0.82) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL31726297 | 0.90 | TOP1 (0.74) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL34463611 | 0.89 | TOP1 (0.78) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL30805390 | 0.89 | TOP1 (0.78) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL22598074 | 0.89 | TOP1 (0.78) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL16649109 | 0.89 | TOP1 (0.78) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL23929259 | 0.89 | TOP1 (1.00) | TOP1DDX5KDM4EMEN1KMT2A | |
| SCHEMBL23963902 | 0.89 | TOP1 (1.00) | TOP1DDX5KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235686-A1 | FLUOROCAMPTOTHECIN COMPOUNDS, CONJUGATES, AND METHODS THEREOF | Aarvik Therapeutics, Inc. (US) | 2025-11-13 | — | — | WO | claimed |
| WO-2025235686-A1 | FLUOROCAMPTOTHECIN COMPOUNDS, CONJUGATES, AND METHODS THEREOF | Aarvik Therapeutics, Inc. (US) | 2025-11-13 | — | — | WO | disclosed |