SCHEMBL31726478

SCHEMBL31726478

O=C(O)COCCOCC(=O)NC[C@@]12CO[C@@H](O1)[C@H](Nc1cccc(C(F)(F)F)n1)[C@@H](O)[C@H]2O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ASGR1 P07306 12/20 0.37
▸ IRAK4 Q9NWZ3 1/20 0.33
▸ HCRTR1 O43613 1/20 0.33
▸ HCRTR2 O43614 1/20 0.33
▸ TAS2R14 Q9NYV8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30063180 0.79 ASGR1 (0.52) ASGR1IRAK4HCRTR1HCRTR2TAS2R14
SCHEMBL24725263 0.79 ASGR1 (0.52) ASGR1IRAK4HCRTR1HCRTR2TAS2R14
SCHEMBL31376879 0.76 ASGR1 (0.46) ASGR1IRAK4HCRTR1HCRTR2
SCHEMBL31376918 0.74 ASGR1 (0.42) ASGR1IRAK4HCRTR1HCRTR2TAS2R14
SCHEMBL31376887 0.74 ASGR1 (0.42) ASGR1HCRTR1HCRTR2
SCHEMBL31376897 0.72 ASGR1 (0.45) ASGR1HCRTR1HCRTR2
SCHEMBL31376910 0.71 ASGR1 (0.38) ASGR1
SCHEMBL24725115 0.70 ASGR1 (0.35) ASGR1HCRTR1HCRTR2
SCHEMBL24725419 0.70 ASGR1 (0.34) ASGR1HCRTR1HCRTR2
SCHEMBL31376876 0.69 ASGR1 (0.37) ASGR1IRAK4HCRTR1HCRTR2TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235814-A1 POTENT ASGPR-BINDING HETEROBIFUCTIONAL COMPOUNDS FOR THE DEGRADATION OF TARGETED EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-11-13 — — WO disclosed
WO-2025235797-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS COMPRISING ANTIBODIES FOR THE DEGRADATION OF TARGETED PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-11-13 — — WO disclosed
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