Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.45 |
| ▸ | LCK | P06239 | 11/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | HCK | P08631 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728496 | 0.93 | MAPK14 (0.51) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL31727679 | 0.85 | SMN1; SMN2 (0.55) | MAPK14MAPK13MAPK12MAPK11TP53 | |
| SCHEMBL16321002 | 0.84 | IL2 (0.42) | IL2MAPK14LCKMAPK13EGFR | |
| SCHEMBL12703109 | 0.79 | LMNA (0.51) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL31728413 | 0.79 | MAPK14 (0.70) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL1147098 | 0.79 | MAPK14 (0.70) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL11925387 | 0.77 | PTPN1 (0.59) | KDM4EMAPK14EGFRSMN1; SMN2 | |
| SCHEMBL5052756 | 0.74 | IL2 (0.69) | IL2KDM4EMAPK14LCKMAPK11 | |
| SCHEMBL15705241 | 0.74 | IL2 (0.48) | IL2MAPK14LCKMAPK13EGFR | |
| SCHEMBL11981315 | 0.73 | HTT (0.55) | KDM4EMAPK14LCKMAPK13EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231563-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |
| WO-2025231561-A1 | TERTIARY AMINE-SUBSTITUTED BIPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |