SCHEMBL31727686

SCHEMBL31727686

CC(C)(C)OC(=O)N1CCN(c2ncc(Cl)cc2N2CC[C@@H](F)C2)CC1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
GPR119 Q8TDV5 7/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP3A5 P20815 1/20 0.41
KIT P10721 1/20 0.40
POLB P06746 1/20 0.40
LMNA P02545 1/20 0.40
STS P08842 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31727097 0.88 GPR119 (0.43) NR1H2NR1H3GPR119KIT
SCHEMBL31728011 0.88 GPR119 (0.44) MAPTGPR119CYP3A4CYP3A5
SCHEMBL31727258 0.88 GPR119 (0.44) MAPTGPR119CYP3A4CYP3A5
SCHEMBL31727321 0.81 NR1H2 (0.41) NR1H2NR1H3GPR119MEN1KMT2A
SCHEMBL31727693 0.81 GPR119 (0.44) MAPTNR1H2NR1H3GPR119CYP3A4
SCHEMBL31727079 0.81 GPR119 (0.44) MAPTNR1H2NR1H3GPR119CYP3A4
SCHEMBL899791 0.80 NR1H2 (0.47) MAPTNR1H2NR1H3GPR119MEN1
SCHEMBL2366192 0.80 MEN1 (0.55) MAPTNR1H2NR1H3GPR119MEN1
SCHEMBL31727733 0.80 GPR119 (0.44) MAPTNR1H2NR1H3GPR119LMNA
SCHEMBL31727494 0.79 NR1H2 (0.43) MAPTNR1H2NR1H3GPR119MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025231561-A1 TERTIARY AMINE-SUBSTITUTED BIPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS UNIVERSITE DE MONTREAL (CA) 2025-11-13 WO disclosed