Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.35 |
| ▸ | ABL1 | P00519 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | HCK | P08631 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.30 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.30 |
| ▸ | PRKDC | P78527 | 2/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728101 | 0.81 | SRC (0.34) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31728341 | 0.80 | SRC (0.34) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31728112 | 0.79 | MET (0.33) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31727950 | 0.79 | MET (0.33) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31728979 | 0.78 | SRC (0.39) | SRCABL1PIK3CDEGFRKDR | |
| SCHEMBL31728350 | 0.78 | SRC (0.39) | SRCABL1PIK3CDEGFRKDR | |
| SCHEMBL31728938 | 0.76 | AAK1 (0.31) | — | |
| SCHEMBL31727705 | 0.76 | AAK1 (0.31) | — | |
| SCHEMBL31728872 | 0.76 | AAK1 (0.31) | — | |
| SCHEMBL31728883 | 0.71 | PDE5A (0.49) | SRCABL1PIK3CDEGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |