Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 5/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728939 | 1.00 | POLB (0.41) | POLBPIK3C3JAK2DHFRSRC | |
| SCHEMBL31729155 | 0.89 | JAK2 (0.34) | POLBJAK2SRCTLR7 | |
| SCHEMBL31728183 | 0.89 | JAK2 (0.34) | POLBJAK2SRCTLR7 | |
| SCHEMBL31728400 | 0.89 | JAK2 (0.34) | POLBJAK2SRCTLR7 | |
| SCHEMBL31728708 | 0.79 | JAK2 (0.33) | JAK2SRC | |
| SCHEMBL31728407 | 0.79 | JAK2 (0.33) | JAK2SRC | |
| SCHEMBL31728135 | 0.78 | PDE5A (0.40) | SRC | |
| SCHEMBL31728923 | 0.75 | POLB (0.36) | POLBJAK2 | |
| SCHEMBL31728449 | 0.70 | CLK1 (0.40) | SRCROCK2ROCK1CDC42BPB | |
| SCHEMBL31728043 | 0.69 | LRRK2 (0.31) | SRCTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |