Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 9/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 7/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.32 |
| ▸ | EGFR | P00533 | 6/20 | 0.32 |
| ▸ | HCK | P08631 | 6/20 | 0.32 |
| ▸ | KDR | P35968 | 6/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.32 |
| ▸ | MTOR | P42345 | 6/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 6/20 | 0.32 |
| ▸ | PRKDC | P78527 | 6/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728708 | 1.00 | JAK2 (0.33) | JAK2SRCMETABL1PIK3CD | |
| SCHEMBL31728043 | 0.82 | LRRK2 (0.31) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31728350 | 0.82 | SRC (0.39) | SRCABL1PIK3CDEGFRKDR | |
| SCHEMBL31728979 | 0.82 | SRC (0.39) | SRCABL1PIK3CDEGFRKDR | |
| SCHEMBL31727906 | 0.79 | DRD2 (0.36) | SRCMETABL1PIK3CDEGFR | |
| SCHEMBL31727946 | 0.79 | DRD2 (0.36) | SRCMETABL1PIK3CDEGFR | |
| SCHEMBL31728183 | 0.79 | JAK2 (0.34) | JAK2SRC | |
| SCHEMBL31727907 | 0.79 | POLB (0.41) | JAK2SRC | |
| SCHEMBL31728135 | 0.79 | PDE5A (0.40) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31728811 | 0.77 | SRC (0.36) | SRCABL1PIK3CDEGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |