Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728069 | 0.75 | CLK1 (0.39) | MAP4K4 | |
| SCHEMBL31729167 | 0.75 | MAP4K4 (0.34) | MAP4K4PTPN11 | |
| SCHEMBL31728431 | 0.75 | MAP4K4 (0.34) | MAP4K4PTPN11 | |
| SCHEMBL31728018 | 0.64 | CLK1 (0.36) | PIK3CDMAP4K4 | |
| SCHEMBL31728332 | 0.64 | CLK1 (0.38) | MAP4K4 | |
| SCHEMBL31728133 | 0.64 | CLK1 (0.36) | PIK3CDMAP4K4 | |
| SCHEMBL31728591 | 0.64 | EIF2AK3 (0.39) | PIK3CDMAP4K4 | |
| SCHEMBL31728213 | 0.64 | EIF2AK3 (0.38) | PIK3CD | |
| SCHEMBL31205568 | 0.63 | TRPV1 (0.38) | GRM5 | |
| SCHEMBL31729163 | 0.62 | CLK1 (0.37) | PIK3CDMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |