Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 12/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728431 | 1.00 | MAP4K4 (0.34) | MAP4K4MAP3K12PSEN1PSEN2APH1B | |
| SCHEMBL31728069 | 0.79 | CLK1 (0.39) | MAP4K4MAPK1CLK1 | |
| SCHEMBL31728073 | 0.77 | GPR119 (0.33) | MAP4K4 | |
| SCHEMBL31727962 | 0.75 | PIK3CD (0.35) | MAP4K4PTPN11 | |
| SCHEMBL31728332 | 0.68 | CLK1 (0.38) | MAP4K4CLK1 | |
| SCHEMBL31728133 | 0.68 | CLK1 (0.36) | MAP4K4CLK1 | |
| SCHEMBL31728018 | 0.68 | CLK1 (0.36) | MAP4K4MAPK1CLK1 | |
| SCHEMBL31729228 | 0.67 | LRRK2 (0.39) | — | |
| SCHEMBL31729163 | 0.65 | CLK1 (0.37) | MAP4K4CLK1 | |
| SCHEMBL31066331 | 0.62 | MAP3K12 (0.41) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |