Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.30 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | HCK | P08631 | 2/20 | 0.30 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.30 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.30 |
| ▸ | PRKDC | P78527 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728445 | 0.85 | LRRK2 (0.33) | LRRK2PIK3CDABL1EGFRHCK | |
| SCHEMBL31728513 | 0.78 | — | — | |
| SCHEMBL31727977 | 0.78 | PIK3CD (0.31) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31728587 | 0.75 | SRC (0.31) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31727795 | 0.75 | — | — | |
| SCHEMBL31662093 | 0.75 | LRRK2 (0.51) | LRRK2PIK3CDABL1EGFRHCK | |
| SCHEMBL31727755 | 0.75 | SRC (0.34) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31728370 | 0.72 | SRC (0.30) | SRC | |
| SCHEMBL31662126 | 0.68 | TDP2 (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL21148772 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |