Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25262091 | 0.83 | HRH1 (0.45) | MAPTRAB9ACHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL30978674 | 0.80 | MAPT (0.44) | MAPTRAB9ACHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL27042621 | 0.80 | MAPT (0.44) | MAPTRAB9ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL23087382 | 0.78 | MAPT (0.47) | MAPTRAB9ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL31727158 | 0.77 | MAPT (0.39) | MAPTRAB9ACHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL30328348 | 0.76 | CHRNB2 (0.42) | MGLLCHRNB2CHRNA4 | |
| SCHEMBL28687611 | 0.76 | CHRNB2 (0.53) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28687610 | 0.76 | CHRNB2 (0.53) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL31403570 | 0.76 | MAPT (0.45) | MAPTRAB9ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL10255974 | 0.76 | MAPT (0.45) | MAPTRAB9ACHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235363-A1 | CYCLIN-DEPENDENT KINASE 4 DEGRADERS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-11-13 | — | — | WO | disclosed |