Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727276 | 0.82 | MAPT (0.45) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL10779236 | 0.80 | ALDH1A1 (0.58) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL15570374 | 0.79 | MAPT (0.51) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL31406159 | 0.76 | MAPT (0.51) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL31727334 | 0.76 | CYP1A2 (0.37) | MAPTLMNAALDH1A1S1PR4NPC1 | |
| SCHEMBL29560142 | 0.75 | MAPT (0.45) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL17045565 | 0.75 | MAPT (0.46) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL17045570 | 0.75 | HTT (0.46) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL26776153 | 0.75 | MAPT (0.45) | MAPTLMNAALDH1A1HPGDS1PR4 | |
| SCHEMBL31358001 | 0.72 | MAPT (0.46) | MAPTLMNAALDH1A1HPGDS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231563-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |
| WO-2025231561-A1 | TERTIARY AMINE-SUBSTITUTED BIPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |