Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24917978 | 0.85 | AURKA (0.41) | AURKAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31728095 | 0.82 | NQO2 (0.38) | AURKAALDH1A1MAPTPDE5ANQO2 | |
| SCHEMBL31728053 | 0.82 | PDE5A (0.44) | MAPTPDE5ANQO2EGFRPOLB | |
| SCHEMBL31728867 | 0.79 | AURKA (0.35) | AURKAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31728521 | 0.76 | KMT2A (0.48) | AURKAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31728792 | 0.76 | AURKA (0.41) | AURKAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL26606967 | 0.73 | NQO2 (0.38) | ALDH1A1MAPTNQO2POLBPRNP | |
| SCHEMBL31727841 | 0.73 | AURKA (0.35) | AURKAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31728476 | 0.72 | PDE5A (0.35) | AURKAPDE5AEGFRPOLBKDR | |
| SCHEMBL26847968 | 0.71 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1MAPTNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |