SCHEMBL31728573

SCHEMBL31728573

COC(=O)c1n[nH]c2ccc(Br)c(C)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.50
▸ STAT3 P40763 1/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ LRRK2 Q5S007 1/20 0.44
▸ KDM4C Q9H3R0 1/20 0.41
▸ FLT3 P36888 1/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ MAPT P10636 2/20 0.35
▸ F2 P00734 2/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ CDC7 O00311 1/20 0.35
▸ NR4A2 P43354 1/20 0.35
▸ CSNK2A2 P19784 1/20 0.35
▸ KDR P35968 1/20 0.35
▸ CSNK2B P67870 1/20 0.35
▸ CSNK2A1 P68400 1/20 0.35
▸ ALPL P05186 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2599805 0.82 KDM4E (0.60) KDM4ESTAT3HIF1ALRRK2KDM4C
SCHEMBL25206400 0.74 KDM4E (0.55) KDM4ESTAT3HIF1ALRRK2KDM4C
SCHEMBL18512239 0.72 KDM4E (0.42) KDM4ESTAT3HIF1ALRRK2KDM4C
SCHEMBL14271999 0.72 KDM4E (0.59) KDM4ESTAT3HIF1ALRRK2KDM4C
SCHEMBL2862825 0.72 KDM4E (0.59) KDM4ESTAT3HIF1ALRRK2KDM4C
SCHEMBL4291226 0.72 KDM4E (0.63) KDM4ESTAT3HIF1AFLT3CDC7
SCHEMBL7737920 0.72 KDM4E (0.59) KDM4ESTAT3HIF1ALRRK2KDM4C
SCHEMBL4791540 0.72 KDM4E (0.59) KDM4ESTAT3HIF1ALRRK2KDM4C
SCHEMBL20531481 0.71 KDM4E (0.48) KDM4ESMN1; SMN2MAPTKMT2APOLB
SCHEMBL31459515 0.71 KDM4C (0.50) KDM4ESTAT3HIF1AKDM4CFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025236004-A1 STAT6 INHIBITORS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2025-11-13 — — WO disclosed
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