Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 6/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728529 | 0.83 | SRC (0.39) | MEN1HPGDKMT2ALIMK1PDE5A | |
| SCHEMBL31729240 | 0.82 | PIK3CD (0.37) | LIMK1SRCEPHB4PIK3CDPIK3CA | |
| SCHEMBL31728359 | 0.81 | EPHB4 (0.36) | SRCEPHB4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31727952 | 0.80 | EIF2AK3 (0.42) | LIMK1PDE5ASRCEPHB4PIK3CB | |
| SCHEMBL31729134 | 0.80 | GSK3B (0.41) | MEN1HPGDKMT2ALIMK1PDE5A | |
| SCHEMBL31728634 | 0.79 | PDE4A (0.37) | SRCEPHB4PIK3CAEGFRKDR | |
| SCHEMBL31729194 | 0.79 | EIF2AK3 (0.38) | PDE5ASRCEPHB4PIK3CDPIK3CA | |
| SCHEMBL31728766 | 0.78 | PIK3CD (0.38) | LIMK1SRCEPHB4PIK3CDPIK3CA | |
| SCHEMBL31727817 | 0.78 | FYN (0.48) | LIMK1PDE5ASRCABL1EGFR | |
| SCHEMBL31728213 | 0.75 | EIF2AK3 (0.38) | MEN1HPGDKMT2ALIMK1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |