Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728121 | 0.79 | CD274 (0.31) | — | |
| SCHEMBL31728800 | 0.79 | CRHR1 (0.39) | SRCEGFRKDREPHB4PIK3CA | |
| SCHEMBL31729240 | 0.72 | PIK3CD (0.37) | SRCEGFRKDREPHB4PIK3CA | |
| SCHEMBL31728766 | 0.68 | PIK3CD (0.38) | SRCEGFREPHB4PIK3CARET | |
| SCHEMBL31729235 | 0.67 | P2RX4 (0.37) | KDR | |
| SCHEMBL31728359 | 0.67 | EPHB4 (0.36) | SRCEGFRKDREPHB4PIK3CA | |
| SCHEMBL31728529 | 0.66 | SRC (0.39) | SRCEGFRKDREPHB4PIK3CA | |
| SCHEMBL15741371 | 0.66 | SRC (0.52) | SRCEGFRERBB2PIK3CA | |
| SCHEMBL31727895 | 0.65 | PIK3CD (0.38) | SRCPIK3CALRRK2RET | |
| SCHEMBL31729194 | 0.65 | EIF2AK3 (0.38) | SRCEGFRERBB2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |