Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.39 |
| ▸ | ABL1 | P00519 | 11/20 | 0.39 |
| ▸ | EGFR | P00533 | 11/20 | 0.39 |
| ▸ | HCK | P08631 | 11/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.39 |
| ▸ | MTOR | P42345 | 11/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 11/20 | 0.39 |
| ▸ | PRKDC | P78527 | 11/20 | 0.39 |
| ▸ | KDR | P35968 | 10/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728970 | 0.82 | CASR (0.36) | CASRJAK2 | |
| SCHEMBL31729218 | 0.81 | CASR (0.34) | CASR | |
| SCHEMBL31728379 | 0.81 | JAK2 (0.36) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728736 | 0.81 | JAK2 (0.36) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728811 | 0.74 | SRC (0.36) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728341 | 0.69 | SRC (0.34) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31727755 | 0.69 | SRC (0.34) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728569 | 0.68 | NQO2 (0.44) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL23989358 | 0.66 | CASR (0.34) | CASRJAK2ALDH1A1LMNATDP1 | |
| SCHEMBL31727802 | 0.64 | SRC (0.34) | SRCPIK3CDABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |