Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728432 | 0.85 | ERBB2 (0.30) | EPHA2KDRERBB2FLT1EPHB4 | |
| SCHEMBL31728366 | 0.85 | ERBB2 (0.30) | EPHA2KDRERBB2FLT1EPHB4 | |
| SCHEMBL31729294 | 0.76 | EPHA2 (0.31) | EPHA2KDRERBB2FLT1EPHB4 | |
| SCHEMBL31728862 | 0.73 | — | — | |
| SCHEMBL31727993 | 0.73 | — | — | |
| SCHEMBL31728913 | 0.68 | MET (0.31) | — | |
| SCHEMBL31727899 | 0.62 | PIK3CD (0.31) | KDREPHB4 | |
| SCHEMBL31728875 | 0.61 | SLC6A4 (0.38) | KDR | |
| SCHEMBL31728840 | 0.60 | ALOX5AP (0.39) | KDREPHB4 | |
| SCHEMBL31728973 | 0.58 | ERBB2 (0.34) | EPHA2KDRERBB2FLT1EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |