Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 11/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728418 | 0.82 | CHRM4 (0.33) | IP6K1DGAT1MAP4K4PIK3R2CLK1 | |
| SCHEMBL31727908 | 0.79 | KCNH2 (0.36) | DGAT1MAP4K4PIK3CDCLK1 | |
| SCHEMBL31728617 | 0.77 | PIK3CD (0.49) | DGAT1PIK3CD | |
| SCHEMBL31728332 | 0.73 | CLK1 (0.38) | MAP4K4HTTCLK1 | |
| SCHEMBL31729239 | 0.69 | CNR2 (0.53) | DGAT1PIK3R2KDM4EALDH1A1MAPT | |
| SCHEMBL31727998 | 0.68 | MAP4K4 (0.49) | IP6K1DGAT1MAP4K4 | |
| SCHEMBL31728069 | 0.67 | CLK1 (0.39) | MAP4K4CLK1 | |
| SCHEMBL31727887 | 0.67 | STK4 (0.53) | MAP4K4PIK3R2CLK1 | |
| SCHEMBL31728133 | 0.64 | CLK1 (0.36) | MAP4K4PIK3CDCLK1 | |
| SCHEMBL31728018 | 0.64 | CLK1 (0.36) | MAP4K4KDM4EHPGDNPSR1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |