Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728418 | 0.78 | CHRM4 (0.33) | DGAT1 | |
| SCHEMBL31729258 | 0.77 | IP6K1 (0.35) | PIK3CDDGAT1 | |
| SCHEMBL31727908 | 0.77 | KCNH2 (0.36) | PIK3CDDGAT1PIK3CAPIK3CGPIK3CB | |
| SCHEMBL31728332 | 0.73 | CLK1 (0.38) | — | |
| SCHEMBL31729228 | 0.69 | LRRK2 (0.39) | PIK3CDPIK3CAPIK3CBMTOR | |
| SCHEMBL31728602 | 0.67 | CNR2 (0.49) | DGAT1 | |
| SCHEMBL31728069 | 0.67 | CLK1 (0.39) | — | |
| SCHEMBL31729239 | 0.67 | CNR2 (0.53) | PIK3CDDGAT1PIK3CAPIK3CGPIK3CB | |
| SCHEMBL19279703 | 0.65 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL24195918 | 0.65 | F10 (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |