Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192196 | 0.83 | PDE2A (0.37) | PDE2ALRRK2GAASMN1; SMN2NR3C1 | |
| SCHEMBL30968152 | 0.76 | PDE2A (0.39) | PDE2AGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8089905 | 0.74 | PDE2A (0.40) | PDE2AGAASMN1; SMN2NR3C1KMT2A | |
| SCHEMBL30259549 | 0.72 | PDE2A (0.39) | PDE2AGAASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL26527418 | 0.72 | PDE2A (0.39) | PDE2AGAASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL31729399 | 0.72 | PDE2A (0.36) | PDE2AGAAKMT2AMEN1 | |
| SCHEMBL31728695 | 0.70 | CSNK1A1 (0.39) | PDE2AGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29345860 | 0.70 | HSD17B10 (0.37) | KDM4EALDH1A1LMNAMAPK1NPC1 | |
| SCHEMBL31729103 | 0.69 | PDE2A (0.36) | PDE2AGAAKMT2A | |
| SCHEMBL31729408 | 0.69 | PDE2A (0.36) | PDE2AGAASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235331-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRAZOLOPYRIMIDINE DERIVATIVES FOR DEGRADING CERTAIN CYCLIN-DEPENDENT KINASE VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |