SCHEMBL3172992

SCHEMBL3172992

CCC1=CC(=O)NC1=O.CCOC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.35
MEN1 O00255 5/20 0.35
MAPT P10636 5/20 0.35
KDM4E B2RXH2 4/20 0.35
ALOX15 P16050 1/20 0.35
POLB P06746 3/20 0.35
ALDH1A1 P00352 5/20 0.34
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
GAA P10253 1/20 0.33
HTT P42858 2/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
LMNA P02545 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
OPRM1 P35372 1/20 0.31
TSHR P16473 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL28123766 0.82 FGFR1 (0.32)
Benzene SCHEMBL27704544 0.82
SCHEMBL28201436 0.80
Hydrochloric Acid SCHEMBL28905030 0.80
Water SCHEMBL28091835 0.80
SCHEMBL8081015 0.78 SMN1; SMN2 (0.44) KMT2AKDM4EALDH1A1GAALMNA
SCHEMBL28775948 0.78 SMN1; SMN2 (0.31) KMT2AMEN1KDM4EALDH1A1
SCHEMBL27840190 0.74 GSK3A (0.46) KMT2AMEN1MAPTKDM4EALOX15
SCHEMBL987749 0.73 CHRNB2 (0.40) KMT2AKDM4EALOX15ALDH1A1GAA
Pyrrole SCHEMBL2280196 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051665-B1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME ALBEMARLE CORP (US) 2006-07-12 EP claimed
US-6555593-B1 Maleimides with a benzophenone compound/hydrogen atom donor sensitizer system activated by irradiation ALBEMARLE CORPORATION 2003-04-29 US claimed
US-6369124-B1 Polymerization processes using aliphatic maleimides FIRST CHEMICAL CORPORATION 2002-04-09 US claimed
US-20020019453-A1 Polymerization processes using aliphatic maleimides FIRST CHEMICAL CORPORATION 2002-02-14 US claimed
EP-1051665-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME First Chemical Corporation (US) 2000-11-15 EP claimed
WO-1999039247-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME FIRST CHEMICAL CORPORATION (US) 1999-08-05 WO claimed
WO-1998007759-A9 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES 1998-06-11 WO claimed
WO-1998007759-A1 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES FIRST CHEMICAL CORPORATION (US) 1998-02-26 WO claimed
EP-1952184-B1 PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE TRANSITIONS OPTICAL INC (US) 2021-08-11 EP disclosed
US-7811480-B2 Photochromic optical article TRANSITIONS OPTICAL, INC. (US) 2010-10-12 US disclosed
US-7649027-B2 having juts via photopolymerization in supercritical carbon dioxide; calcining KANSAI PAINT CO., LTD. (JP) 2010-01-19 US disclosed
US-20090023830-A1 POLYMER AND PROCESS FOR PRODUCING POLYMER KANSAI PAINT CO., LTD. (JP) 2009-01-22 US disclosed
EP-1952184-A2 PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE TRANSITIONS OPTICAL, INC. (US) 2008-08-06 EP disclosed
US-7258437-B2 Photochromic multifocal optical article TRANSITIONS OPTICAL, INC. (US) 2007-08-21 US disclosed
EP-1051665-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME First Chemical Corporation (US) 2000-11-15 EP disclosed
WO-2000020517-A2 RADIATION-CURABLE COMPOSITIONS COMPRISING MALEIMIDE COMPOUNDS AND METHOD FOR PRODUCING A SUBSTRATE WITH A CURED LAYER DSM N.V. (NL) 2000-04-13 WO disclosed
US-6034150-A Polymerization processes using aliphatic maleimides UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2000-03-07 US disclosed
WO-1999039247-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME FIRST CHEMICAL CORPORATION (US) 1999-08-05 WO disclosed
WO-1998007759-A9 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES 1998-06-11 WO disclosed
WO-1998007759-A1 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES FIRST CHEMICAL CORPORATION (US) 1998-02-26 WO disclosed