Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17713798 | 1.00 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL17713799 | 1.00 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL317317 | 1.00 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL19612933 | 1.00 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL19612935 | 1.00 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL20515840 | 0.95 | PRKCA (0.51) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL9219827 | 0.92 | PRKCA (0.53) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL9641266 | 0.92 | PRKCA (0.47) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL7057551 | 0.92 | PRKCA (0.47) | PRKCAPRKCEPRKCQPRKCDCNR1 | |
| SCHEMBL7057555 | 0.92 | PRKCA (0.47) | PRKCAPRKCEPRKCQPRKCDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590644-A1 | SN-2-MONOACYLGLYCEROLS AND LIPID MALABSORPTION | Nestec S.A. (CH) | 2013-05-15 | — | — | EP | claimed |
| US-20130109753-A1 | SN-2-MONOACYLGLYCEROLS AND LIPID MALABSORPTION | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2013-05-02 | — | — | US | claimed |
| EP-2409695-A1 | Sn-2-Monoacylglycerols and lipid malabsorption | Beth Israel Deaconess Medical Center, Inc. (US) | 2012-01-25 | — | — | EP | claimed |
| WO-2012004234-A1 | SN-2-MONOACYLGLYCEROLS AND LIPID MALABSORPTION | NESTEC S.A. (CH) | 2012-01-12 | — | — | WO | claimed |
| US-20180280337-A1 | NUTRITIONAL COMPOSITIONS COMPRISING SN-1(3) MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF GROWTH DELAY IN INFANTS OR CHILDREN | Société des Produits Nestlé S.A. (CH) | 2018-10-04 | — | — | US | disclosed |
| US-10039742-B2 | Sn-2-monoacylglycerols and lipid malabsorption | NESTEC S.A. (CH) | 2018-08-07 | — | — | US | disclosed |
| US-9980934-B2 | Monoacylglycerols for use in conjunction with a lipase inhibitor and/or diets low in fat and/or calories | NESTEC S.A. (CH) | 2018-05-29 | — | — | US | disclosed |
| US-20180133190-A1 | MONOACYLGLYCEROLS AND FAT-SOLUBLE NUTRIENTS FOR USE IN THE TREATMENT OF NUTRIENT DEFICIENCY FROM MALDIGESTION | NESTEC S.A. (CH) | 2018-05-17 | — | — | US | disclosed |
| EP-2409695-B1 | SN-2-MONOACYLGLYCEROLS AND LIPID MALABSORPTION | BETH ISRAEL DEACONESS MEDICAL CT INC (US) | 2018-03-21 | — | — | EP | disclosed |
| US-20170332691-A1 | NUTRITIONAL COMPOSITIONS COMPRISING SN-1 (3) MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF MALABSORPTION OR MALDIGESTION IN INFANTS OR YOUNG CHILDREN | Société des Produits Nestlé S.A. (CH) | 2017-11-23 | — | — | US | disclosed |
| US-20170296507-A1 | SN-2-MONOACYLGLYCEROLS AND LIPID MALABSORPTION | STEPAN COMPANY | 2017-10-19 | — | — | US | disclosed |
| EP-3212180-A1 | NUTRITIONAL COMPOSITIONS COMPRISING SN-1(3) MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF GROWTH DELAY IN INFANTS OR CHILDREN | Nestec S.A. (CH) | 2017-09-06 | — | — | EP | disclosed |
| US-20160263073-A1 | MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF MALABSORPTION HAVING A MECHANICAL BASIS | NESTEC S.A. (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160250174-A1 | MONOACYLGLYCEROLS FOR USE IN CONJUNCTION WITH A LIPASE INHIBITOR AND/OR DIETS LOW IN FAT AND/OR CALORIES | Société des Produits Nestlé S.A. (CH) | 2016-09-01 | — | — | US | disclosed |
| WO-2016066459-A1 | NUTRITIONAL COMPOSITIONS COMPRISING SN-1(3) MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF GROWTH DELAY IN INFANTS OR CHILDREN | NESTEC S.A. (CH) | 2016-05-06 | — | — | WO | disclosed |
| US-20150224079-A1 | SN-2-MONOACYLGYCEROLS AND LIPID MALABSORPTION | STEPAN COMPANY | 2015-08-13 | — | — | US | disclosed |
| US-9034917-B2 | Sn-2-monoacylglycerols and lipid malabsorption | NESTEC S.A. (CH) | 2015-05-19 | — | — | US | disclosed |
| US-20140142169-A1 | SN-2-MONOACYLGLYCEROLS AND LIPID MALABSORPTION | NESTEC S.A. (CH) | 2014-05-22 | — | — | US | disclosed |
| US-20130109753-A1 | SN-2-MONOACYLGLYCEROLS AND LIPID MALABSORPTION | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2409695-A1 | Sn-2-Monoacylglycerols and lipid malabsorption | Beth Israel Deaconess Medical Center, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |