Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171106 | 1.00 | MAPT (0.47) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL23113073 | 0.86 | PAX8 (0.40) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL31733218 | 0.85 | PAX8 (0.39) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL23112951 | 0.85 | PAX8 (0.39) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL31005213 | 0.84 | TP53 (0.39) | MAPTGAATHRBRAB9AALDH1A1 | |
| SCHEMBL1557348 | 0.84 | PAX8 (0.38) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL31733034 | 0.84 | PAX8 (0.38) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL31733024 | 0.83 | CYP1A2 (0.41) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL31733187 | 0.81 | BACE1 (0.36) | MAPTATMGAAMAPK1THRB | |
| SCHEMBL23673260 | 0.80 | PAX8 (0.38) | MAPTATMGAAMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025236100-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2025-11-20 | — | — | WO | disclosed |