Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 15/20 | 0.47 |
| ▸ | SCN7A | Q01118 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902504 | 1.00 | BACE1 (0.58) | BACE1KMT2APTPN1CNR2SCN9A | |
| SCHEMBL1285735 | 0.85 | BACE1 (0.56) | BACE1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL5474090 | 0.84 | BACE1 (0.51) | BACE1CNR2SCN9ASCN7AKCNH2 | |
| SCHEMBL16966898 | 0.79 | SCN9A (0.75) | SCN9ASCN7AKCNH2SCN5ASCN10A | |
| SCHEMBL30310860 | 0.78 | KMT2A (0.55) | BACE1KMT2ASCN9A | |
| SCHEMBL31733680 | 0.78 | BACE1 (0.55) | BACE1PTPN1SCN9ASCN7AKCNH2 | |
| Hydrochloric Acid SCHEMBL31733671 | 0.77 | BACE1 (0.53) | BACE1PTPN1SCN9ASCN7AKCNH2 | |
| Hydrochloric Acid SCHEMBL23294630 | 0.77 | ATF4 (0.54) | BACE1SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL5460532 | 0.76 | KMT2A (0.45) | BACE1KMT2APTPN1CNR2SCN9A | |
| SCHEMBL14597743 | 0.76 | KDM4C (0.60) | SCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239937-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-3676297-B1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC (US) | 2023-05-17 | — | — | EP | disclosed |