SCHEMBL31734338

SCHEMBL31734338

CC(C)NC1CCN(C(=O)OC(C)(C)C)CC1(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.46
▸ HPGD P15428 1/20 0.45
▸ MAPT P10636 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ RECQL P46063 1/20 0.40
▸ DPP4 P27487 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ PTPN2 P17706 1/20 0.40
▸ PTPN1 P18031 1/20 0.40
▸ PTPN6 P29350 1/20 0.40
▸ STS P08842 4/20 0.39
▸ EPHX2 P34913 1/20 0.39
▸ TRPV3 Q8NET8 1/20 0.38
▸ GPR119 Q8TDV5 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26171864 0.86 EPHX1 (0.45) EPHX1HPGDMAPTALDH1A1NPC1
SCHEMBL29083228 0.86 EPHX1 (0.45) EPHX1HPGDMAPTALDH1A1NPC1
SCHEMBL21649154 0.84 EPHX1 (0.46) EPHX1HPGDMAPTALDH1A1NPC1
SCHEMBL17966353 0.82 KDM4E (0.47) MAPTALDH1A1NPC1MAPK1HTT
SCHEMBL19813102 0.82 KDM4E (0.47) MAPTALDH1A1NPC1MAPK1HTT
SCHEMBL17966352 0.82 KDM4E (0.47) MAPTALDH1A1NPC1MAPK1HTT
SCHEMBL26621385 0.82 KDM4E (0.47) MAPTALDH1A1NPC1MAPK1HTT
SCHEMBL17966350 0.82 KDM4E (0.47) MAPTALDH1A1NPC1MAPK1HTT
SCHEMBL30661567 0.82 KDM4E (0.47) MAPTALDH1A1NPC1MAPK1HTT
SCHEMBL17966348 0.82 KDM4E (0.47) MAPTALDH1A1NPC1MAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242565-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF IN THE PREVENTION OR THERAPY OF DISEASES Samsara Therapeutics Inc. (US) 2025-11-27 — — WO disclosed
EP-4653432-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF IN THE PREVENTION OR THERAPY OF DISEASES Samsara Therapeutics Inc. (US) 2025-11-26 — — EP disclosed
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