Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26171864 | 1.00 | EPHX1 (0.45) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL21649154 | 0.86 | EPHX1 (0.46) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL31734338 | 0.86 | EPHX1 (0.46) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL25185104 | 0.85 | NR1H2 (0.40) | EPHX1HPGDEPHX2USP2SMN1; SMN2 | |
| SCHEMBL17125681 | 0.84 | EPHX1 (0.49) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL4172346 | 0.84 | EPHX1 (0.49) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL21411217 | 0.84 | EPHX1 (0.41) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL15416696 | 0.84 | EPHX1 (0.41) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL17630680 | 0.81 | HPGD (0.47) | EPHX1HPGDRECQLMAPTKDM4E | |
| SCHEMBL1965038 | 0.81 | HPGD (0.47) | EPHX1HPGDRECQLMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783202-A | Thienopyrrole compounds | 吉利德科学公司 | 2023-09-19 | — | — | CN | disclosed |