Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763020 | 0.95 | USP2 (0.55) | USP2HPGDTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL19158577 | 0.89 | USP2 (0.46) | USP2HPGDTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL18390156 | 0.87 | USP2 (0.60) | USP2TSHRCYP3A4CYP2D6HSD17B10 | |
| SCHEMBL18390606 | 0.86 | CYP3A4 (0.48) | USP2HPGDTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL21401558 | 0.85 | USP2 (0.46) | USP2HPGDSMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL18390391 | 0.85 | USP2 (0.70) | USP2HPGDTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL24267542 | 0.84 | HPGD (0.45) | USP2HPGDSMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL10111786 | 0.84 | HPGD (0.45) | USP2HPGDSMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL18389855 | 0.84 | CYP3A4 (0.59) | USP2HPGDTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL18053441 | 0.83 | CYP11B2 (0.48) | USP2TSHRSMN1; SMN2CYP3A4CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245351-A1 | SUBSTITUTED ARYL SULFONAMIDES AND COMPOSITIONS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-11-27 | — | — | WO | disclosed |