Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | OXTR | P30559 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566459 | 0.93 | KDM4E (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31735201 | 0.92 | KDM4E (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31735279 | 0.86 | KMT2A (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL31735378 | 0.86 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31735220 | 0.85 | MEN1 (0.34) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20238565 | 0.84 | KMT2A (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29669086 | 0.84 | KMT2A (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL19631905 | 0.82 | KMT2A (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL19614107 | 0.82 | DHFR (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL19614108 | 0.82 | KDM4E (0.36) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245351-A1 | SUBSTITUTED ARYL SULFONAMIDES AND COMPOSITIONS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-11-27 | — | — | WO | disclosed |