SCHEMBL31735514

SCHEMBL31735514

Cc1c(Nc2ccc3[nH]ccc3c2)cnn(C)c1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 5/20 0.44
▸ BRD9 Q9H8M2 5/20 0.44
▸ KAT2B Q92831 2/20 0.44
▸ PLK2 Q9NYY3 6/20 0.43
▸ LCK P06239 1/20 0.43
▸ KIT P10721 1/20 0.43
▸ FGFR3 P22607 1/20 0.43
▸ FLT3 P36888 1/20 0.43
▸ PLK1 P53350 1/20 0.43
▸ RPS6KA1 Q15418 1/20 0.43
▸ PIM3 Q86V86 1/20 0.43
▸ WNK2 Q9Y3S1 1/20 0.43
▸ P2RX3 P56373 1/20 0.42
▸ BPTF Q12830 6/20 0.42
▸ EGFR P00533 1/20 0.41
▸ NEK2 P51955 1/20 0.41
▸ NEK5 Q6P3R8 1/20 0.41
▸ NEK1 Q96PY6 1/20 0.41
▸ NPC1 O15118 1/20 0.40
▸ MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735737 0.87 BPTF (0.58) BRD4BRD9KAT2BBPTFEGFR
SCHEMBL31735642 0.87 BPTF (0.58) BRD4BRD9KAT2BBPTFEGFR
SCHEMBL31735800 0.83 BRD9 (0.43) BRD4BRD9KAT2BBPTF
SCHEMBL31735885 0.83 BRD4 (0.44) BRD4BRD9KAT2BBPTFEGFR
SCHEMBL31735494 0.81 BRD9 (0.41) BRD4BRD9KAT2BPLK2BPTF
SCHEMBL31735506 0.81 BRD9 (0.41) BRD4BRD9KAT2BBPTF
SCHEMBL31735933 0.81 BRD4 (0.44) BRD4BRD9KAT2BBPTF
SCHEMBL31735443 0.81 EGFR (0.46) PLK2LCKKITFGFR3FLT3
SCHEMBL31735809 0.80 BRD9 (0.43) BRD4BRD9KAT2BBPTF
SCHEMBL31735495 0.80 BRD9 (0.44) BRD4BRD9KAT2BBPTF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
Send feedback