SCHEMBL31735495

SCHEMBL31735495

Cc1c(Nc2cc(Nc3cnn(C)c(=O)c3C)c3cc[nH]c3c2)cnn(C)c1=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BRD9 Q9H8M2 10/20 0.44
▸ BRD4 O60885 9/20 0.44
▸ KAT2B Q92831 4/20 0.41
▸ BPTF Q12830 12/20 0.40
▸ P2RX7 Q99572 1/20 0.36
▸ BRD7 Q9NPI1 2/20 0.35
▸ KAT2A Q92830 1/20 0.35
▸ CECR2 Q9BXF3 1/20 0.35
▸ BRPF1 P55201 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735599 0.88 BRD9 (0.45) BRD9BRD4KAT2BBPTFBRD7
SCHEMBL31735622 0.87 BRD9 (0.43) BRD9BRD4KAT2BBPTFP2RX7
SCHEMBL31735431 0.85 MAPK14 (0.47) BRD9BRD4KAT2BBPTFBRD7
SCHEMBL31735770 0.85 BRD9 (0.38) BRD9BRD4KAT2BBPTFP2RX7
SCHEMBL31735480 0.84 P2RX7 (0.46) BRD9BRD4P2RX7
SCHEMBL31735525 0.83 MAPK14 (0.41) BRD9BRD4KAT2BBPTFBRD7
SCHEMBL31735511 0.83 MAPK14 (0.45) BRD9BRD4KAT2BBPTFP2RX7
SCHEMBL31735450 0.81 BRD4 (0.39) BRD9BRD4KAT2BBPTF
SCHEMBL31735514 0.80 BRD4 (0.44) BRD9BRD4KAT2BBPTF
SCHEMBL31735496 0.79 BRD4 (0.42) BRD9BRD4KAT2BBPTFP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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