SCHEMBL31735595

SCHEMBL31735595

Cc1c(Nc2ccc3[nH]cc(C#N)c3c2)cnn(C)c1=O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ XDH P47989 1/20 0.44
▸ BRD4 O60885 6/20 0.41
▸ BRD9 Q9H8M2 5/20 0.41
▸ KAT2B Q92831 2/20 0.40
▸ PRKCQ Q04759 1/20 0.38
▸ BPTF Q12830 7/20 0.38
▸ LRRK2 Q5S007 3/20 0.37
▸ PFKFB2 O60825 1/20 0.37
▸ PFKFB1 P16118 1/20 0.37
▸ PFKFB3 Q16875 1/20 0.37
▸ BCL6 P41182 1/20 0.37
▸ CCNT1 O60563 1/20 0.36
▸ CDK9 P50750 1/20 0.36
▸ HASPIN Q8TF76 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735704 0.84 BRD9 (0.47) BRD4BRD9KAT2BBPTF
SCHEMBL31735961 0.82 BRD4 (0.41) BRD4BRD9KAT2BBPTF
SCHEMBL31735627 0.80 BRD9 (0.49) BRD4BRD9KAT2BBPTFBCL6
SCHEMBL31735628 0.79 SYK (0.47) BRD4BRD9KAT2BBPTF
SCHEMBL31735366 0.78 BRD4 (0.44) BRD4BRD9KAT2BBPTF
SCHEMBL31735514 0.78 BRD4 (0.44) BRD4BRD9KAT2BBPTF
SCHEMBL31735885 0.73 BRD4 (0.44) BRD4BRD9KAT2BBPTF
SCHEMBL31735689 0.72 BRD9 (0.44) BRD4BRD9KAT2BBPTF
SCHEMBL31735933 0.71 BRD4 (0.44) BRD4BRD9KAT2BBPTF
SCHEMBL31735702 0.68 BRD4 (0.70) BRD4BRD9KAT2BBPTF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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