SCHEMBL31735688

SCHEMBL31735688

COCCn1ccc2c(Cl)cc(Nc3cnn(C)c(=O)c3C)cc21

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 11/20 0.42
▸ BRD9 Q9H8M2 10/20 0.42
▸ KAT2B Q92831 5/20 0.40
▸ BPTF Q12830 10/20 0.38
▸ BRD7 Q9NPI1 2/20 0.36
▸ KAT2A Q92830 1/20 0.36
▸ CECR2 Q9BXF3 1/20 0.36
▸ BRPF1 P55201 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735592 0.88 BRD9 (0.42) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735825 0.87 BRD9 (0.40) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735396 0.86 BRD9 (0.40) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735819 0.85 BRD4 (0.41) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735786 0.85 BRD9 (0.39) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735723 0.85 BRD4 (0.39) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735588 0.83 BRD9 (0.43) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735746 0.83 BRD4 (0.42) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735860 0.83 BRD4 (0.44) BRD4BRD9KAT2BBPTFBRD7
SCHEMBL31735517 0.83 BRD4 (0.41) BRD4BRD9KAT2BBPTFBRD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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