SCHEMBL31735746

SCHEMBL31735746

COCCn1ccc2c(Nc3cnn(C)c(=O)c3C)c(Cl)ccc21

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 17/20 0.42
▸ BRD9 Q9H8M2 14/20 0.42
▸ KAT2B Q92831 7/20 0.39
▸ BRPF1 P55201 1/20 0.38
▸ BRD7 Q9NPI1 1/20 0.38
▸ BPTF Q12830 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735653 0.90 BRD4 (0.45) BRD4BRD9KAT2BBRPF1BRD7
SCHEMBL31735860 0.88 BRD4 (0.44) BRD4BRD9KAT2BBRPF1BRD7
SCHEMBL31735819 0.86 BRD4 (0.41) BRD4BRD9KAT2BBRPF1BRD7
SCHEMBL31735688 0.83 BRD4 (0.42) BRD4BRD9KAT2BBRPF1BRD7
SCHEMBL31735390 0.79 BRD9 (0.42) BRD4BRD9KAT2BBRD7BPTF
SCHEMBL31735425 0.78 BRD4 (0.41) BRD4BRD9KAT2BBRPF1BRD7
SCHEMBL31735683 0.78 BRAF (0.38) BRD4BRD9KAT2B
SCHEMBL31735592 0.77 BRD9 (0.42) BRD4BRD9KAT2BBRPF1BRD7
SCHEMBL31735513 0.77 BRD9 (0.42) BRD4BRD9KAT2BBRPF1BRD7
SCHEMBL31735711 0.73 BRD4 (0.51) BRD4BRD9KAT2BBRPF1BRD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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