SCHEMBL31735693

SCHEMBL31735693

Clc1cc2[nH]ccc2c(Cl)c1Br

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.48
RHEB Q15382 11/20 0.41
ALDH1A1 P00352 1/20 0.40
AHR P35869 5/20 0.39
P2RX7 Q99572 1/20 0.37
NR4A2 P43354 2/20 0.35
CYP2A6 P11509 1/20 0.35
CMA1 P23946 1/20 0.35
F7 P08709 1/20 0.35
LTA4H P09960 1/20 0.35
F3 P13726 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30678169 0.84 CSNK2A1 (0.44) CSNK2A1RHEBALDH1A1AHRNR4A2
SCHEMBL25258324 0.81 RHEB (0.49) CSNK2A1RHEBALDH1A1AHRP2RX7
SCHEMBL29345927 0.77 CSNK2A1 (0.46) CSNK2A1RHEBALDH1A1AHRNR4A2
SCHEMBL1020404 0.73 RHEB (0.50) CSNK2A1RHEBALDH1A1AHRNR4A2
SCHEMBL29506983 0.73 RHEB (0.50) CSNK2A1RHEBALDH1A1AHRNR4A2
SCHEMBL1075774 0.71 RHEB (0.47) CSNK2A1RHEBALDH1A1AHRNR4A2
SCHEMBL1065531 0.71 AHR (0.52) CSNK2A1RHEBAHRP2RX7NR4A2
SCHEMBL30774212 0.71 RHEB (0.47) CSNK2A1RHEBALDH1A1AHRNR4A2
SCHEMBL15797442 0.71 P2RX7 (0.51) CSNK2A1RHEBALDH1A1P2RX7F7
SCHEMBL31416308 0.70 RHEB (0.50) RHEBAHRP2RX7NR4A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 WO disclosed