SCHEMBL31735722

SCHEMBL31735722

Cn1nc(C2CCC2)c(C(N)=O)c1N

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RET P07949 2/20 0.38
PDPK1 O15530 1/20 0.34
LRRK2 Q5S007 1/20 0.32
SRC P12931 1/20 0.31
PROKR1 Q8TCW9 1/20 0.31
POLB P06746 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1814028 0.95 RET (0.42) RETPDPK1FAAH
SCHEMBL5230043 0.95 RET (0.42) RETPDPK1FAAH
SCHEMBL31735662 0.93 RET (0.39) RETPDPK1LRRK2SRCPOLB
SCHEMBL27471498 0.79 PDPK1 (0.31) RETPDPK1
SCHEMBL27471489 0.79 PDPK1 (0.31) RETPDPK1
SCHEMBL26287413 0.79 PDPK1 (0.31) RETPDPK1
SCHEMBL27471507 0.78 CHRNB2 (0.33) PDPK1
SCHEMBL27471512 0.78 PDPK1 (0.31) PDPK1
SCHEMBL26287415 0.78 PDPK1 (0.31) PDPK1
SCHEMBL26287404 0.78 PDPK1 (0.31) PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245472-A1 COMPOUNDS AND RELATED METHODS USEFUL FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES REMIX THERAPEUTICS INC. (US) 2025-11-27 WO disclosed