SCHEMBL31735780

SCHEMBL31735780

CC(=O)OCCn1ccc2cc(Nc3cnn(C)c(=O)c3Cl)ccc21

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BPTF Q12830 14/20 0.51
▸ KAT2B Q92831 7/20 0.47
▸ BRD9 Q9H8M2 7/20 0.47
▸ BRD4 O60885 6/20 0.47
▸ KAT2A Q92830 1/20 0.46
▸ CECR2 Q9BXF3 1/20 0.46
▸ BRD7 Q9NPI1 1/20 0.46
▸ P2RX3 P56373 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735448 0.88 MAOA (0.41) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735793 0.88 BPTF (0.51) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735881 0.86 BPTF (0.53) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735828 0.82 BPTF (0.61) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735824 0.82 BPTF (0.52) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735675 0.81 BPTF (0.54) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735856 0.81 BPTF (0.51) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735470 0.80 BPTF (0.43) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735875 0.80 BPTF (0.53) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735577 0.79 BPTF (0.60) BPTFKAT2BBRD9BRD4KAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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