SCHEMBL31735781

SCHEMBL31735781

Cn1c(-c2ccccc2)cc2c(Nc3ccncn3)nc(Cl)cc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FYN P06241 3/20 0.51
▸ TGFBR1 P36897 2/20 0.42
▸ LYN P07948 1/20 0.41
▸ SRC P12931 1/20 0.41
▸ BTK Q06187 1/20 0.41
▸ KDR P35968 1/20 0.39
▸ ACP1 P24666 1/20 0.39
▸ CCNA2 P20248 1/20 0.38
▸ CDK2 P24941 1/20 0.38
▸ CCNA1 P78396 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SLC2A1 P11166 1/20 0.36
▸ SCN9A Q15858 1/20 0.36
▸ TGFBR2 P37173 1/20 0.36
▸ HRH4 Q9H3N8 1/20 0.35
▸ JAK2 O60674 1/20 0.35
▸ TYK2 P29597 1/20 0.35
▸ SLC34A1 Q06495 2/20 0.35
▸ CCNB2 O95067 1/20 0.35
▸ CDK1 P06493 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735626 0.80 FYN (0.44) FYNTGFBR1LYNSRCBTK
SCHEMBL31735620 0.80 CYP1A2 (0.43) FYNTGFBR1LYNSRCBTK
SCHEMBL16331435 0.78 FYN (0.49) FYNTGFBR1KDRCCNA2CDK2
SCHEMBL31735942 0.76 KMT2A (0.51) KMT2ASLC2A1CCNB2CDK1CCNB1
SCHEMBL16332442 0.72 FYN (0.41) FYNTGFBR1SRCCCNA2CDK2
SCHEMBL16331769 0.72 HPGD (0.43) FYNLYNSRCBTKKDR
SCHEMBL16331663 0.70 FYN (0.41) FYNTGFBR1KDRCCNA2CDK2
SCHEMBL16331628 0.69 HPGD (0.50) KMT2ASLC2A1CCNB2CDK1CCNB1
SCHEMBL18613220 0.67 FYN (1.00) FYNLYNSRCBTKKDR
SCHEMBL1062987 0.67 TGFBR1 (0.68) TGFBR1SRCKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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