SCHEMBL31735934

SCHEMBL31735934

COCCn1ccc2cc(Nc3cnn(C)c(=O)c3C(C)C)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GLO1 Q04760 1/20 0.38
▸ BRD9 Q9H8M2 5/20 0.36
▸ EGFR P00533 2/20 0.36
▸ BRPF1 P55201 1/20 0.36
▸ BPTF Q12830 9/20 0.36
▸ BRD4 O60885 4/20 0.35
▸ KAT2B Q92831 4/20 0.35
▸ NTSR1 P30989 1/20 0.35
▸ HTR6 P50406 1/20 0.35
▸ KAT2A Q92830 1/20 0.34
▸ CECR2 Q9BXF3 1/20 0.34
▸ BRD7 Q9NPI1 1/20 0.34
▸ MTNR1A P48039 1/20 0.34
▸ MTNR1B P49286 1/20 0.34
▸ HDAC3 O15379 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ HDAC2 Q92769 1/20 0.34
▸ HDAC8 Q9BY41 1/20 0.34
▸ HDAC6 Q9UBN7 1/20 0.34
▸ NCOR2 Q9Y618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735425 0.87 BRD4 (0.41) GLO1BRD9EGFRBRPF1BPTF
SCHEMBL31735793 0.86 BPTF (0.51) BRD9BPTFBRD4KAT2BKAT2A
SCHEMBL31735612 0.86 BPTF (0.49) GLO1BRD9EGFRBPTFBRD4
SCHEMBL31735678 0.85 EGFR (0.39) GLO1BRD9EGFRBRPF1BPTF
SCHEMBL31735472 0.83 BCL6 (0.40) GLO1BRD9EGFRBPTFBRD4
SCHEMBL31735768 0.81 GLO1 (0.40) GLO1EGFRNTSR1HTR6MTNR1A
SCHEMBL31735643 0.79 GLO1 (0.44) GLO1EGFRNTSR1HTR6MTNR1A
SCHEMBL31735470 0.79 BPTF (0.43) GLO1BRD9BPTFBRD4KAT2B
SCHEMBL31735517 0.79 BRD4 (0.41) BRD9BRPF1BPTFBRD4KAT2B
SCHEMBL31735856 0.78 BPTF (0.51) BRD9BPTFBRD4KAT2BKAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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