Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725520 | 0.87 | CYP17A1 (0.48) | AAK1CYP17A1RXFP1BRAFKCNQ4 | |
| SCHEMBL12519275 | 0.87 | AAK1 (0.44) | AAK1NPC1RAB9ACYP17A1RXFP1 | |
| SCHEMBL29840249 | 0.87 | AAK1 (0.46) | AAK1NPC1RAB9ACYP17A1RXFP1 | |
| SCHEMBL24195942 | 0.85 | AAK1 (0.46) | AAK1NPC1RAB9ACYP17A1RXFP1 | |
| SCHEMBL31662566 | 0.85 | AAK1 (0.48) | AAK1CYP17A1MEN1KMT2ALMNA | |
| SCHEMBL19502094 | 0.85 | LMNA (0.44) | AAK1NPC1RAB9ACYP17A1RXFP1 | |
| SCHEMBL5785487 | 0.85 | AAK1 (0.48) | AAK1CYP17A1MEN1KMT2ALMNA | |
| SCHEMBL31376047 | 0.84 | AAK1 (0.45) | AAK1NPC1RAB9ACYP17A1RXFP1 | |
| SCHEMBL30947444 | 0.84 | CYP17A1 (0.42) | AAK1NPC1RAB9ACYP17A1RXFP1 | |
| SCHEMBL25159676 | 0.84 | AAK1 (0.46) | AAK1NPC1RAB9ACYP17A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |