Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 18/20 | 0.48 |
| ▸ | EIF2S1 | P05198 | 17/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736026 | 1.00 | EIF2AK3 (0.48) | EIF2AK3EIF2S1EGFRERBB2 | |
| SCHEMBL31736142 | 0.92 | CSF1R (0.43) | EIF2AK3EIF2S1EGFRERBB2 | |
| SCHEMBL31736188 | 0.92 | CSF1R (0.43) | EIF2AK3EIF2S1EGFRERBB2 | |
| SCHEMBL31736263 | 0.89 | EIF2AK3 (0.47) | EIF2AK3EIF2S1 | |
| SCHEMBL31735971 | 0.89 | EIF2AK3 (0.47) | EIF2AK3EIF2S1 | |
| SCHEMBL31736631 | 0.89 | EIF2AK3 (0.39) | EIF2AK3EIF2S1EGFRERBB2 | |
| SCHEMBL31736156 | 0.89 | EIF2AK3 (0.52) | EIF2AK3EIF2S1 | |
| SCHEMBL31736378 | 0.89 | EIF2AK3 (0.39) | EIF2AK3EIF2S1EGFRERBB2 | |
| SCHEMBL31736185 | 0.89 | EIF2AK3 (0.52) | EIF2AK3EIF2S1 | |
| SCHEMBL31736380 | 0.87 | EIF2AK3 (0.48) | EIF2AK3EIF2S1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |