Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28729081 | 0.89 | SYK (0.41) | MAPK1 | |
| SCHEMBL22895358 | 0.89 | SYK (0.41) | MAPK1 | |
| SCHEMBL31619957 | 0.81 | MAPK1 (0.64) | IGF1RMAPK8IKBKBMAPK1HRH3 | |
| SCHEMBL14397338 | 0.81 | HDAC1 (0.45) | IGF1RMAPK8IKBKBMAPK1HRH3 | |
| SCHEMBL31736992 | 0.81 | MAPK1 (0.64) | IGF1RMAPK8IKBKBMAPK1HRH3 | |
| SCHEMBL4701457 | 0.81 | IGF1R (0.46) | IGF1RMAPK8IKBKBMAPK1HRH3 | |
| SCHEMBL22057257 | 0.79 | ENPP2 (0.47) | DDB1CRBNSLC18A3SIGMAR1 | |
| SCHEMBL29763119 | 0.79 | KDM4E (0.48) | IGF1RMAPK8IKBKBMAPK1HRH3 | |
| SCHEMBL1073617 | 0.79 | KDM4E (0.64) | MAPK8IKBKBMAPK1HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL23131043 | 0.78 | ENPP2 (0.46) | DDB1CRBNSLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245178-A1 | PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | INNOVO THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |